I just fed your information into the [Steve Morse's Relationship Calculator][1] in this order: 1. parent 2. sister 3. husband 4. daughter 5. daughter and it returned that your parent's sister's husband's daughter's daughter is to you a > ??? (non-blood relative) If you ignore the "husband" that led to the step then you get (as @TomH said) > 1st cousin once removed (blood relative) If you really want a label for the non-blood relationship between you, then I think the following would be as good as any: > step 1st cousins once removed [1]: http://stevemorse.org/relation/calculator.html